1.the monster was not allowed to run, if caught running he lost points.
2.instead of scientists, we had terroists vs monster vs guards. the terrorists want the monster for themselves and the guards want it dead.
Guards need to find the weapon; terrorists need to find a tranq. for the monster. Optionally you can make it harder for the guards by making them have to build the weapon i.e. more than one part.
3.guards and terrorists respawn. seprate dead-zones.
5.more guards then terrorists.
6.terrorists need to tranq and get the monster out to a dead-zone.(monster can walk or be dragged, draging not recommended)
7.guards need to kill monster
8.(option)the EX weapon was a cheap blowgun we found at a kmart. that was pretty funny when the guards found a blowgun with a peice of paper saying “We told you it was experimental.” on it.

We played 3 terroist, 5 guards, 1 monster. it was a blast.

Me and my friends spent about 4 hours playing your scenario (and slight variations of it) yesterday – we started off with only four people, but found it improved quite drastically when you have a monster, two insane scientists and 4 security guards [Editor: That's a good idea - I have modified the original recommended team member numbers to reflect this. Thanks for the report!], as the mix up in a small area is hilarious – friendly fire, an accidental shot which turns out to be the best shot of the afternoon and while the monster was strolling happily along with with the MP5K blasting at full auto, he got taken out by a non-hop-up air cocking berretta!”